Difference between revisions of "Border Disease Virus"
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(New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Flaviviridae |subtext1=FLAVIVIRIDAE |pagetype =Bugs }} <br> ====Hosts==== *Sheep *Goats ====Pathogenesis==== *T...) |
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*Tropism: fetal lymphoid tissue, hair follicles, and CNS | *Tropism: fetal lymphoid tissue, hair follicles, and CNS | ||
*Causes '''abortion''' or '''weak lambs''' | *Causes '''abortion''' or '''weak lambs''' | ||
| − | *'''Hairy shaker lambs''': born with hair instead of wool | + | *'''Hairy shaker lambs''': born with [[Skin Congenital and Hereditary - Pathology#Hypertrichosis|hair instead of wool]] |
**'''Immunotolerant''' status when exposed in mid-third of gestation | **'''Immunotolerant''' status when exposed in mid-third of gestation | ||
**Also associated with '''cerebellar hypoplasia''' | **Also associated with '''cerebellar hypoplasia''' | ||
Revision as of 20:36, 21 October 2008
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This article is still under construction. |
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Hosts
- Sheep
- Goats
Pathogenesis
- Tropism: fetal lymphoid tissue, hair follicles, and CNS
- Causes abortion or weak lambs
- Hairy shaker lambs: born with hair instead of wool
- Immunotolerant status when exposed in mid-third of gestation
- Also associated with cerebellar hypoplasia
Epidemiology
- Can cause significant problems to a flock
- First reported on Welsh borders
Diagnosis
- Clinical: abortion and hairy shaker lambs
- Confirmation by serology: ELISA for virus antigen
Control
- No UK vaccine
- Vaccines available in USA and Europe
- Blood testing sheep can aid in culling seropositive ewes