Bovine Herpesvirus 1
Revision as of 17:29, 29 October 2008 by Bepocock (talk | contribs) (New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Herpesviridae |subtext1=HERPESVIRUSES |pagetype =Bugs }} <br> ====Antigenicity==== *Two different viruses: **Infe...)
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Antigenicity
- Two different viruses:
- Infectious Bovine Rhinotracheitis (IBR): aerosol transfer
- Infectrious Pustular Vulvovaginitis (IPV): venereal transfer
Pathogenesis
IBR:
- Dypsnoea, anorexia
- Rhinotrachietis that can develop into bronchopneumonia
- Up to 75% mortality if concurrent with BVDV, caused by meningo-encephalitis
IPV:
- Painful genital lesions
- Impaired reproductive performance
- Frequent micturition
Diagnosis
- Virus isolation and immunofluorescence
Control
- Vaccination:
- Two live attenuated vaccines are available in the UK, one is temperature-sensitive
- Both given intranasally
- Neither protect against re-infection when given during clinical outbreak, but can lessen the severity of the disease
- Inactivated vaccines: intranasal/intramuscular administration
- gE deletion makes this a marker vaccine
- ELISA for gE deletion can enable culling of carrier animals
- Two live attenuated vaccines are available in the UK, one is temperature-sensitive
- IPV has mostly been made obsolete by AI