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(BIV)
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*Lentivirus (non-oncogenic)
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*Causes a persistent viral infection and lymphocytosis
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==Description==
*Immunocompromised cattle may develop secondary infections
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Bovine Imunodeficiency Virus (BIV) is a Lentivirus (non-oncogenic) which causes a persistent viral infection in cattle worldwide. It was first isolated in 1969 from a cow with a wasting syndrome.
*The transmission is not well known, but the following possibilities are being researched:
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==Pathogenesis==
**Through milk
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The mechanism of transfer is not well knonw,but the following posibilites are being researched :
**Through infected semen (e.g.artificial insemination)
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* Transplacental
**Placental transfer
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* Transmammary
*Diagnosis:
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* Vertical transfer through infected Semenn (e.g. Artificial inseminatio)
**Western Blot
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==Clinical Signs==
**PCR
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Bovine immunodeficiency Virus is not associated with a specific disease in cattle but has been associated with the folowing signs:
[[Category:Secondary Immunodeficiency]][[Category:Cattle]][[Category:To Do - Blood]][[Category:To Do - Clinical]]
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* Decreased milk yield
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* clinical immunodeficiency
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* encephalitis
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* bovine paraplegic syndrome
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* skin infections
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* emaciation
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==Diagnosis==
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*Western Blot
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*PCR
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==Treatment and Control==
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The Incidence of Bovine immunodeficiency virus appears to be low (1%) although can reach >15 % in some herds
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==References==
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* Merck & Co (2008) '''The Merck Veterinary Manual (Eighth Edition)''' ''Merial''
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* Quinn, P.J., Markey, B.K., Carter, M.E., Donnelly, W.J., Leonard, F.C. (2007) '''Veterinary Microbiology and Microbial Disease''' ''Blackwell Publishing''
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[[Category:Secondary Immunodeficiency]][[Category:Cattle]][[Category:To Do - Blood]][[Category:To Do - Katie]]
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