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Bullous Pemphigoid (view source)

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'''Pathogenesis:''' [[Type II Hypersensitivity|Type II hypersensitivity]]?

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~~'''Pathogenesis~~:~~'''~~ [[~~Type II Hypersensitivity~~|~~Type II hypersensitivity~~]]

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*Dogs and horses

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*Involves oral cavity, mucocutaneous junctions, groin and axilla

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*Subepidermal vesicles and bullae

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*Antibodies bound to basement membrane

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*Grossly:

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**Similar to [[Pemphigus|Pemphigus vulgaris]]

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*Microscopically:

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**Bullae containing fibrin, [[Neutrophils|neutrophils]] or [[Eosinophils|eosinophils]]

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**Basement membrane forms floor of bullae and roof is lined with basal cells

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*Bullae may rupture -> ulcers

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[[Category:Integumentary System - Autoimmune Reactions]]

[[Category:Antibody Mediated Autoimmune Diseases]]

[[Category:To Do - Blood]][[Category:To Do - Clinical]]

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