Difference between revisions of "Burkholderia pseudomallei"
Jump to navigation
Jump to search
(Created page with '*Causes melioidosis - endemic in Asia and Australia *Primarily infects rodents *Pathogenesis: **Infe…') |
|||
| Line 20: | Line 20: | ||
**ELISA, complement fixation and indirect haemagglutination tests for serum antibodies | **ELISA, complement fixation and indirect haemagglutination tests for serum antibodies | ||
*Treatment/control: slaughter of infected animals where exotic[[Category:Pseudomonas_and_Burkholderia_species]][[Category:Rodents]] | *Treatment/control: slaughter of infected animals where exotic[[Category:Pseudomonas_and_Burkholderia_species]][[Category:Rodents]] | ||
| + | [[Category:To_Do_-_Bacteria]] | ||
Revision as of 10:56, 25 June 2010
- Causes melioidosis - endemic in Asia and Australia
- Primarily infects rodents
- Pathogenesis:
- Infection via ingestion, inhalation or skin wounds from environment
- Exotoxin, dermonecrotic protease and lecithinase implicated in pathogenicity
- Strain virulence and host immunosuppression important
- Clinical infections:
- Opportunistic infection with stress and immunosuppression predisposing to disease
- Abscesses develop in many organs including lungs, spleen, liver, joints, CNS, upper respiratory tract
- Chronic, debilitating, progressive disease with long incubation period
- Many animal species susceptible
- Referred to as pseudoglanders in horses
- Diagnosis:
- Specimens: pus from abscesses, affected tissues, blood
- Fluorescent antibody technique on tissue smears
- Blood agar and MacConkey agar plates, incubated aerobically
- Colonies have musty smell
- Lactose fermentation on MacConkey
- Slide agglutination
- ELISA, complement fixation and indirect haemagglutination tests for serum antibodies
- Treatment/control: slaughter of infected animals where exotic