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Formation of the neuroectoderm occurs as a result of the folding of the neural plate due to the presence of the Lateral Plate Mesoderm (LPM) factor.  
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Formation of the neuroectoderm occurs as a result of the folding of the neural plate due to the presence of the Lateral Plate Mesoderm (LPM) factor. The edges of the neural plate begin to fold upwards and inwards, eventually leading to the formation of a neural crest and tube. LPM also initiates the formation of epidermis from ectoderm and therefore areas of ectoderm dorsal to the neural tube differentiate into epidermis.
[[Image:WIKIVETformationofneuraltissue.jpg|thumb|centre|300px|Formation of Neural Tissue - © Sophie Stenner]]
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[[Image:WIKIVETformationofneuraltissue.jpg|thumb|left|400px|Formation of Neural Tissue - © Sophie Stenner]]
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[[Image:WIKIVETneuraltubeformation.jpg|thumb|right|400px|Neural Tube Formation - © Sophie Stenner]]
 
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[[Image:WIKIVETneuraltubeformation.jpg|thumb|centre|300px|Neural Tube Formation - © Sophie Stenner]]
   
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LPM causes ectoderm to form epidermis. To overcome this in development the notochord secretes a LPM factor antagonist allowing the formation of neuroectoderm directly above it. This forms the '''neural plate''' and folds to form the '''neural tube'''.
   
[[Image:WIKIVETneuraltubeformation.jpg]]
 
[[Image:WIKIVETneuraltubeformation.jpg]]
 
[[Image:WIKIVETbraindifferentiation.jpg|thumb|right|150px|Brain Differentiation - © Sophie Stenner]]
 
[[Image:WIKIVETbraindifferentiation.jpg|thumb|right|150px|Brain Differentiation - © Sophie Stenner]]
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