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Category:Cell Mediated Autoimmune Diseases (view source)

Revision as of 15:01, 11 August 2010

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===1. [[Rheumatoid Arthritis]]===

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===2. ~~Diabetes Mellitus type I===~~

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===2.

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~~[[Image:Diabetes Mellitus Type IV hypersensitivity.jpg|right|thumb|150px|Diabetes Mellitus-Brian Catchpole RVC 2008]]~~

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~~'''Pathogenesis:'''~~

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* [[Type IV Hypersensitivity - WikiBlood|Type IV hypersensitivity]]

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* The CTLs think that all the beta cells in the pancreas are infected by a virus, as it wrongly detects a self antigen presented by the MHC class I on the surface of the cell as foreign.

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* Autoreactive CD8+ CTLs are inadvertently activated, destroying the beta cells, thus preventing the secretion of insulin and causing diabetes type 1 (see diagram).

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~~[[Category:Cell Mediated Autoimmune Diseases]][[Category:To Do - Blood]]~~

===3. Hypothyroidism (lymphocytic throiditis)===

Bara

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