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| − | ==[[Pancreas - Nodular Hyperplasia]]== | + | {{frontpage |
| | + | |pagetitle =Pancreas - Hyperplastic and Neoplastic Pathology |
| | + | |pagebody = |
| | + | |contenttitle =Content |
| | + | |contentbody =<big><b> |
| | + | <categorytree mode=pages>Pancreas - Hyperplastic and Neoplastic Pathology</categorytree> |
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| | + | </b></big> |
| | + | |logo =path-logo.png |
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| − | ==Neoplasia==
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| − | *Originates from the exocrine tissue or excretory ducts
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| − | *Neoplasia of the '''[[Pancreas - Anatomy & Physiology#Endocrine|Islet cells]]''' is rare but may cause hypoglycaemia due to overproduction of insulin
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| − | ==Adenoma==
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| − | [http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=7754 Image of multifocal pancreatic adenoma in a dog from Cornell Veterinary Medicine]
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| − | *Very rare
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| − | *May be difficult to distinguish from nodular hyperplasia
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| − | *Single and larger nodules than normal [[Pancreas - Anatomy & Physiology|pancreas]]
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| − | ==Carcinoma==
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| − | [[Image:Pancreatic carcinoma.jpg|right|thumb|100px|<small><center>Pancreatic carcinoma (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
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| − | [http://w3.vet.cornell.edu/nst/nst.asp?Fun=Image&imgID=11616 Image of haemorrhage and pancreatic carcinoma in a cat from Cornell Veterinary Medicine]
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| − | *In older dogs, more common in Airedale terriers, rare in cats, other species too
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| − | *Tend to arise centrally in the gland
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| − | *Highly invasive and infiltrative
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| − | *Metastases to the [[Liver - Anatomy & Physiology|liver]], visceral serosa, abdominal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]], [[Adrenal Glands - Anatomy & Physiology|adrenals]] etc.
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| − | *Similar to malignant ovarian tumours - implant on the [[Peritoneal cavity - Anatomy & Physiology|peritoneum]]
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| − | ===Gross appearance===
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| − | [[Image:Pancreatic carcinoma histo.jpg|right|thumb|100px|<small><center>Pancreatic carcinoma (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
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| − | *Usually spherical nodules with adhesions to nearby structures
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| − | *Single or multiple, variable size
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| − | *Greyish or yellow fibrous tissue - firm on cutting
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| − | *May show internal necrosis and haemorrhage
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| − | *Some tumours may contain cysts wih mucinous content
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| − | *Adhesions may occur
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| − | ===Microscopic appearance===
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| − | *May be well differentiated with normal acini and ducts
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| − | *Or diffuse sheet of undifferentiated cells
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