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'''A 6-year-old Holstein cow, which calved 36 hr earlier, is presented in sternal recumbency, profoundly depressed, dehydrated, afebrile (38.5°C,101.3°F)), with toxic mucous membranes, an elevated heart rate of 96 beats per minute, and an increased respiratory rate (34 breaths per minute). The udder is soft but a pale, serum-like, secretion can be drawn from one quarter.'''

'''A 6-year-old Holstein cow, which calved 36 hr earlier, is presented in sternal recumbency, profoundly depressed, dehydrated, afebrile (38.5°C,101.3°F), with toxic mucous membranes, an elevated heart rate of 96 beats per minute, and an increased respiratory rate (34 breaths per minute). The udder is soft but a pale, serum-like, secretion can be drawn from one quarter.'''

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Treatment of endotoxic shock (coliform mastitis) includes intravenous injection of a NSAID, repeated 12 hr later. <br><br>

Treatment of endotoxic shock (coliform mastitis) includes intravenous injection of a NSAID, repeated 12 hr later. <br><br>

Hypertonic saline (7.2%) infusion at a dose rate of 5mL/kg (3 L for 600 kg cow) over 5–7 minutes is achieved through a 13-gauge<ref>Minor point, only catheters 12 or 14 gauge are available in the UK.</ref> 10cm jugular catheter. <br><br>

Hypertonic saline (7.2%) infusion at a dose rate of 5mL/kg (3 L for 600 kg cow) over 5–7 minutes is achieved through a 13-gauge¹ 10cm jugular catheter. <br><br>

Access to 30–60 L of warm water, which may contain electrolytes, must be provided although not all cows drink; some clinicians recommend stomach tubing volumes up to 30–40 L. <br><br>

Access to 30–60 L of warm water, which may contain electrolytes, must be provided although not all cows drink; some clinicians recommend stomach tubing volumes up to 30–40 L. <br><br>

This cow made a full recovery. Mastitis caused by ''Streptococcus uberis'' can present with many of the clinical features of coliform mastitis and it may prove prudent to administer a broad-spectrum antibiotic both parenterally and by intramammary infusion.  

This cow made a full recovery. Mastitis caused by ''Streptococcus uberis'' can present with many of the clinical features of coliform mastitis and it may prove prudent to administer a broad-spectrum antibiotic both parenterally and by intramammary infusion.  

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{{Comments

{{Comments

|by = Nick Lyons MA VetMB CertCHP MRCVS

|by = Nick Lyons MA VetMB CertCHP MRCVS

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