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Chronic Fibrosing Interstitial Pneumonia - Donkey (view source)
Revision as of 21:19, 18 October 2010
, 21:19, 18 October 2010no edit summary
==Introduction==
A large number of cases of IPF have been diagnosed ''post-mortem'' at [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary]. There is chronic fibrosis of the sub-pleural and interstitial lung tissue. As yet the aetiology is undetermined. A progressive on-going irritation to the lung is likely to be responsible, but whether this is allergic or toxic is unclear.
==Clinical Signs==
The clinical signs depend on the stage of the disease and are similar to that of [[Recurrent Airway Obstruction - Donkey|RAO]], with '''tachypnoea and dyspnoea'''. There may be '''nostril flare''' and, rarely, a '''cough''' is heard. Auscultation of the lungs reveals a variety of
'''adventitious sounds'''.
==Diagnosis==
[[Image:Pulmonary fibrosis donkey.jpg|right|thumb|250px|<small><center>Pulmonary fibrosis (Image courtesy of [http://drupal.thedonkeysanctuary.org.uk The Donkey Sanctuary])</center></small>]]
It is difficult to diagnose the condition with certainty ''ante-mortem'', but lack of response to treatment often indicates pulmonary fibrosis is present. Despite the chronic nature of the disease, a number of animals present with an acute dyspnoea, regardless of therapy; these carry a very poor prognosis for survival despite therapy.
At '''''post-mortem''''' the lesions vary in severity from focal areas of fibrosis to large areas of generalised fibrosis with severe sub-pleural fibrosis. Airway inflammation is usually limited to the areas of collapsed and fibrosed lung, unlike the widespread inflammation seen in [[Recurrent Airway Obstruction - Donkey|RAO]].
==Treatment==
Treatment to optimise remaining lung function is similar to that as described for [[Recurrent Airway Obstruction - Donkey#Treatment|RAO]], and may be required for life. '''Secondary bacterial bronchitis''' is a common feature of IPF and [[Antibiotics|antibiotic therapy]] is often required.
==Literature Search==
[[File:CABI logo.jpg|left|90px]]
Use these links to find recent scientific publications via CAB Abstracts (log in required unless accessing from a subscribing organisation).
<br><br><br>
[http://www.cabdirect.org/search.html?rowId=1&options1=AND&q1=pneumonia&occuring1=title&rowId=2&options2=AND&q2=donkeys&occuring2=od&rowId=3&options3=AND&q3=&occuring3=freetext&x=34&y=16&publishedstart=yyyy&publishedend=yyyy&calendarInput=yyyy-mm-dd&la=any&it=any&show=all Pneumonia in donkeys publications]
==References==
* Thiemann, A. (2008) Respiratory problems In Svendsen, E.D., Duncan, J. and Hadrill, D. (2008) ''The Professional Handbook of the Donkey'', 4th edition, Whittet Books, Chapter 7
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==References==
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[[Category:Donkey]]
[[Category:Lower_Respiratory_Tract_Disorders_-_Donkey]]