Coronaviridae
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Introduction
Morphology
- Large, spherical enveloped RNA viruses
- Identified by their crowns: long bulbous widely-spaced spikes
Virulence and Pathogenesis
- Pathogenesis varies widely based on each virus, but most commonly cause respiratory and enteric disturbances
- Those described here will be the enteric variety
Virus by Species
Transmissible Gastroenteritis Virus of Pigs (TGEV)
Feline Infections Peritonitis (FIP)
- Coronavirus contributes to undifferentiated neonatal calf diarrhoea, a mixed viral enteritis in calves.
- Transmissible Gastro-Enteritis (TGE) in pigs
- Winter dysentery in cattle.
- Feline Infectious Peritonitis.
- Calf coronavirus may contribute to Enzootic pneumonia of calves
- Porcine respiratory coronavirus (PRCV) in pig pneumonia
- Porcine encephalomyelitis, apart from neuronal destruction, may also cause myofibre necrosis