Difference between revisions of "Culicoides Hypersensitivity"

From WikiVet English
Jump to navigation Jump to search
Line 3: Line 3:
 
Also known as '''Sweet Itch'''
 
Also known as '''Sweet Itch'''
  
*Usually involves [[Skin Immunologic - Pathology#Type I reactions|Type I reaction]] and [[Skin Immunologic - Pathology#Type IV reactions|Type IV reaction]]  due to salivary antigens of ''Culicoides'' sp.
+
==Description==
*May be seasonally recurring or continuous depending on climate
+
Culicoides hypersensitivity, commonly referred to as 'Sweet itch' is an intensely pruritic dermatitis of horses caused by a hypersensitivity reaction to the saliva of biting ''Culicoides'' midges. The condition may be seasonally recurring or continuous depending on the climate
*Grossly:
+
 
 +
==Pathogenesis==
 +
The condition is thought to occur due to both immediate (Type 1) and delayed (Type 4) hypersensitivity reactions to Culicoides salivary proteins. These proteins are injected during feeding and susceptible animals respond to them by producing IgE antibodies.
 +
 
 +
 
 +
*Grossly:s
 
**Papules, crusts, alopecia, excoriations, lichenification
 
**Papules, crusts, alopecia, excoriations, lichenification
 
*Microscopically:
 
*Microscopically:

Revision as of 11:59, 1 September 2010



Also known as Sweet Itch

Description

Culicoides hypersensitivity, commonly referred to as 'Sweet itch' is an intensely pruritic dermatitis of horses caused by a hypersensitivity reaction to the saliva of biting Culicoides midges. The condition may be seasonally recurring or continuous depending on the climate

Pathogenesis

The condition is thought to occur due to both immediate (Type 1) and delayed (Type 4) hypersensitivity reactions to Culicoides salivary proteins. These proteins are injected during feeding and susceptible animals respond to them by producing IgE antibodies.


  • Grossly:s
    • Papules, crusts, alopecia, excoriations, lichenification
  • Microscopically:
    • Superficial and dep perivascular dermatitis
    • Many eosinophils
    • Epidermal hyperplasia
    • Hyperkeratosis
    • Dermal fibrosis
    • Possibly eosinophilic folliculitis, intraepidermal pustules and eosinophilic granulomas