Changes

Where the clinical course has been more prolonged, a '''sero-fibrinous perihepatitis and pericarditis''' is common  and large volumes of '''straw coloured ascites''' often found. '''Pulmonary oedema, liver lesions and catarrhal enteritis''' may also be present. '''Diptheritic lesions''' and ulcers may be seen in the mouth, pharynx and oesophagus – these are usually due to secondary infection.

Where the clinical course has been more prolonged, a '''sero-fibrinous perihepatitis and pericarditis''' is common  and large volumes of '''straw coloured ascites''' often found. '''Pulmonary oedema, liver lesions and catarrhal enteritis''' may also be present. '''Diptheritic lesions''' and ulcers may be seen in the mouth, pharynx and oesophagus – these are usually due to secondary infection.

Histopathology reveals '''degenerative muocardial cell changes with loss of striation, fatty infiltration and intranuclear inclusion bodies'''. Similar changes are seen in intestinal and smooth muscle cells. Hepatocyte '''vacuolation and fatty infiltration''' dominate the liver. The hepatocytes also sometimes contain '''eosinophilic inclusion-like bodies'''. Pancreatic cells are often necrotic, shrunken and also infiltrated by fat deposits.

Histopathology reveals '''degenerative myocardial cell changes with loss of striation, fatty infiltration and intranuclear inclusion bodies'''. Similar changes are seen in intestinal and smooth muscle cells. Hepatocyte '''vacuolation and fatty infiltration''' dominate the liver. The hepatocytes also sometimes contain '''eosinophilic inclusion-like bodies'''. Pancreatic cells are often necrotic, shrunken and also infiltrated by fat deposits.

==Treatment==

==Treatment==