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| '''Tests to rule out'''
 
| '''Tests to rule out'''
 
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|Cervical vertebral malformation (CVM, cervical compressive myeolpathy, Wobblers)
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+
|Symmetrical gait deficits, worse in pelvic limbs (3 in Hahn p603) with spasticity and dysmetria,  good retention of strength,  no muscle wasting (Furr) '''NB:can be concurrent with EPM''' (Hahn)
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+
|Standing plain lateral rads of C1 to T1 (Hahn in Furr)
 
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|-
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|WNV encephalitis
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+
|Systemically ill, pyrexia and changes in leukogram
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+
|CSF abnormal, difficult if horse not febrile and no excessive muscle fasciculations, IgM capture ELISA
 
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|-
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|EEE
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|Systemically ill, pyrexia and changes in leukogram, abnormal motor function (Long), rapidly progressive (seino, p134)
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+
|CSF abnormal
 
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|-
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|WEE
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+
|Systemically ill, pyrexia and changes in leukogram, abnormal motor function (Long)
 
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|VEE
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|Systemically ill, pyrexia and changes in leukogram
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+
|IgM ELISA (Bertone)
 
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|Equine herpesvirus-1 myeloencephalopathy
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|Sudden onset and early stabilization of neuro signs, multiple horses affected, recent fever, abortion (14 in Wilson and Pusterla p615) dysuria not often seen in EPM
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|PCR (Furr)
 
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Includes virtually all diseases of the CNS (Furr)
 
Includes virtually all diseases of the CNS (Furr)
   −
Cervical vertebral malformation (CVM, cervical compressive myeolpathy, Wobblers) (but symmetrical gait deficits, worse in pelvic limbs (3 in Hahn p603) with spasticity and dysmetria,  good retention of strength,  no muscle wasting (Furr)), standing plain lateral rads of C1 to T1 (Hahn in Furr), can be concurrent with EPM (Hahn)
+
 
Infectious diseases of the CNS (systemically ill, pyrexia and changes in leukogram)
  −
WNV encephalitis - CSF abnormal, difficult if horse not febrile and no excessive muscle fasciculations, IgM capture ELISA
  −
EEE - CSF abnormal, abnormal motor function (Long), rapidly progressive (seino, p134)
  −
WEE – abnormal motor function (Long)
  −
VEE – IgM capture ELISA (Bertone)
  −
Equine herpesvirus-1 myeloencephalopathy – sudden onset and early stabilization of neuro signs, multiple horses affected, recent fever, abortion (14 in Wilson and Pusterla p615) dysuria not often seen in EPM , PCR (Furr)
   
Rabies – rapid progression (Sommardahl), behavioural alterations, depression, seizure, coma (Long), post-mortem dx (Sommardahl)
 
Rabies – rapid progression (Sommardahl), behavioural alterations, depression, seizure, coma (Long), post-mortem dx (Sommardahl)
 
Multifocal disease, ataxia and muscle atrophy also found with:
 
Multifocal disease, ataxia and muscle atrophy also found with:
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