Difference between revisions of "Ethylene Glycol Toxicity"

From WikiVet English
Jump to navigation Jump to search
Line 5: Line 5:
  
 
==Signalment==
 
==Signalment==
Dogs, cats, birds, other.<ref>'''The 5-Minute Veterinary Consult, Canine and Feline''' (Second Edition),''lippencott, Williams and Wilkins </ref>,     
+
Dogs, cats, birds, other.<ref name=''multiple''>'''The 5-Minute Veterinary Consult, Canine and Feline''' (Second Edition),''lippencott, Williams and Wilkins </ref>,     
  
 
==Diagnosis==
 
==Diagnosis==

Revision as of 14:55, 30 October 2010



Introduction

Ethylene Glycol is a sweet tasting fluid that is the main constituent of anti-freeze products.[1]. Consequently in colder climates ethylene glycol toxicity is frequently encountered in practice. It has a relatively low minimum lethal dose, and its sweet, palatable taste makes it attractive to dogs, cats and other small animals. [2]


Signalment

Dogs, cats, birds, other.[3],

Diagnosis

Clinical Signs

Laboratory Tests

Pathology

Treatment

Ethylene Glycol is a weak acid. Therefore in order to increase the rate of renal clearance sodium bicarbonate can be administered to dogs. Intravenous administration of sodium bicarbonate at a concentration of 1-2 mmol/kg every 3 to 6 hours achieves sufficient alkalinisation of the urine.[4]

Prognosis

References

  1. The 5-Minute Veterinary Consult, Canine and Feline, Lippencott, Williams and Wilkins
  2. The 5-Minute Veterinary Consult, Canine and Feline (Second Edition),lippencott, Williams and Wilkins
  3. The 5-Minute Veterinary Consult, Canine and Feline (Second Edition),lippencott, Williams and Wilkins
  4. Canine Medicine and Therapeutics (Fourth Edition, 1998),Blackwell Science, p1049