Difference between revisions of "Ethylene Glycol Toxicity"

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==Introduction==
 
==Introduction==
Ethylene Glycol is a sweet tasting fluid that is the main constituent of anti-freeze products.<ref name="multiple">'''The 5-Minute Veterinary Consult, Canine and Feline''', ''Lippencott, Williams and Wilkins''</ref>. Consequently in colder climates ethylene glycol toxicity is frequently encountered in practice. It has a relatively low minimum lethal dose, and its sweet, palatable taste makes it attractive to dogs, cats and other small animals. <ref>'''The 5-Minute Veterinary Consult, Canine and Feline''' (Second Edition),''lippencott, Williams and Wilkins </ref>     
+
Ethylene Glycol is a sweet tasting fluid that is the main constituent of anti-freeze products.<ref name="multiple">'''The 5-Minute Veterinary Consult, Canine and Feline''', ''Lippencott, Williams and Wilkins''</ref>. Consequently in colder climates ethylene glycol toxicity is frequently encountered in practice. It has a relatively low minimum lethal dose, and its sweet, palatable taste makes it attractive to dogs, cats and other small animals. <ref>'''The 5-Minute Veterinary Consult, Canine and Feline''' (Second Edition),''Lippencott, Williams and Wilkins </ref>     
  
  
 
==Signalment==
 
==Signalment==
Dogs, cats, birds, other.<ref name=''multiple''>'''The 5-Minute Veterinary Consult, Canine and Feline''' (Second Edition),''lippencott, Williams and Wilkins </ref>,     
+
Dogs, cats, birds, other.<ref name="multiple">'''The 5-Minute Veterinary Consult, Canine and Feline''' (Second Edition),''Lippencott, Williams and Wilkins </ref>,     
  
 
==Diagnosis==
 
==Diagnosis==

Revision as of 14:56, 30 October 2010



Introduction

Ethylene Glycol is a sweet tasting fluid that is the main constituent of anti-freeze products.[1]. Consequently in colder climates ethylene glycol toxicity is frequently encountered in practice. It has a relatively low minimum lethal dose, and its sweet, palatable taste makes it attractive to dogs, cats and other small animals. [2]


Signalment

Dogs, cats, birds, other.[1],

Diagnosis

Clinical Signs

Laboratory Tests

Pathology

Treatment

Ethylene Glycol is a weak acid. Therefore in order to increase the rate of renal clearance sodium bicarbonate can be administered to dogs. Intravenous administration of sodium bicarbonate at a concentration of 1-2 mmol/kg every 3 to 6 hours achieves sufficient alkalinisation of the urine.[3]

Prognosis

References

  1. 1.0 1.1 The 5-Minute Veterinary Consult, Canine and Feline, Lippencott, Williams and Wilkins Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content
  2. The 5-Minute Veterinary Consult, Canine and Feline (Second Edition),Lippencott, Williams and Wilkins
  3. Canine Medicine and Therapeutics (Fourth Edition, 1998),Blackwell Science, p1049