Feline Herpesvirus 1

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VIRUSES
HERPESVIRUSES



Pathogenesis

  • Upper respiratory tract infection *
  • Erosions can affect the bronchi, resulting in interstitial pneumonia
  • Most common cause of keratitis and corneal ulcers in cat and gummy eyes in kittens
    • Rupture is a particular risk

Epidemiology

  • Widespread
  • Serious infection
  • Latent infection can be reactivated on boarding

Diagnosis

  • Nasal swabs on first week of infection can be cultured for virus isolation

Treatment

For keratitis with corneal ulcers:

  • Subcut omega interferon
  • Topical trifluorothymidine (thymidine analogue) on eyes

Control

  • Killed and live vaccines are available
    • Live vaccines have provoked symptoms in immunosuppressed kittens and are no longer used in the UK