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{{Template:Manson Sparkes}}

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|q1=What is this plant and the likely result following ingestion of it?

|q1=What is this plant and the likely result following ingestion of it?

|a1=

|a1=

The plant is a Tiger Lily and both the leaves and flowers are known to be toxic to cats causing severe ARF, although the precise toxin is unknown. Although highly toxic, recovery is possible in many cases with adequate supportive care.

The plant is a Tiger Lily and both the leaves and flowers are known to be toxic to cats causing severe ARF, although the precise toxin is unknown.  

 

Although highly toxic, recovery is possible in many cases with adequate supportive care.

|l1=House Plant Toxicity

|l1=House Plant Toxicity

|q2=What general supportive treatment should be provided for this toxicity and how should the likely major complications be addressed?

|q2=What general supportive treatment should be provided for this toxicity and how should the likely major complications be addressed?

|a2=

|a2=

Aggressive treatment of ARF involves intravenous fluid administration, with mild volume overload to promote urine production and diuresis. If oliguria persists (<1–2 ml/kg/hr) then furosemide (2–6 mg/kg IV) and/or mannitol (0.25–0.5 g/kg IV) can be administered to promote urine production. Other supportive care such as H2- antagonists, antiemetics, and nutritional support may be required. The major metabolic consequences of ARF are hyperkalaemia and acidosis which can be profound. Mild changes may respond to intravenous fluid therapy but severe changes need prompt therapy. Severe hyperkalaemia (>8 mmol/l [>8 mEq/l]) requires  

Aggressive treatment of ARF involves intravenous fluid administration, with mild volume overload to promote urine production and diuresis.  

0.5–1.0 ml/kg 10% calcium gluconate slowly IV to provide cardioprotection. Sodium bicarbonate (typically 1–2 mmol [mEq] per kg) given slowly IV will help address both acidosis and hyperkalaemia. Additionally 1 g/kg 20% glucose can be given IV with or

 

without approximately 0.2 U/kg soluble insulin to cause cellular uptake of potassium. Careful monitoring of response (potassium, glucose, and acid–base status) is required. Severe acidosis (pH <7.15) requires bicarbonate therapy using 1–2 mmol or mEq per

If oliguria persists (<1–2 ml/kg/hr) then furosemide (2–6 mg/kg IV) and/or mannitol (0.25–0.5 g/kg IV) can be administered to promote urine production. Other supportive care such as H2- antagonists, antiemetics, and nutritional support may be required.  

kg slowly IV or calculated from: 0.3 × bodyweight (kg) × (desired bicarbonate – measured bicarbonate). Half of the calculated dose is given IV over 20–30 minutes and the remainder added to the intravenous fluids. The dose required varies between cases though, and should be adjusted according to response.

 

|l2=Acute Renal Failure

The major metabolic consequences of ARF are hyperkalaemia and acidosis which can be profound.  

 

Mild changes may respond to intravenous fluid therapy but severe changes need prompt therapy.  

 

Severe hyperkalaemia (>8 mmol/l [>8 mEq/l]) requires 0.5–1.0 ml/kg 10% calcium gluconate slowly IV to provide cardioprotection. Sodium bicarbonate (typically 1–2 mmol [mEq] per kg) given slowly IV will help address both acidosis and hyperkalaemia.  

 

Additionally 1 g/kg 20% glucose can be given IV with or without approximately 0.2 U/kg soluble insulin to cause cellular uptake of potassium. Careful monitoring of response (potassium, glucose, and acid–base status) is required.  

 

Severe acidosis (pH <7.15) requires bicarbonate therapy using 1–2 mmol or mEq per kg slowly IV or calculated from: 0.3 × bodyweight (kg) × (desired bicarbonate – measured bicarbonate). Half of the calculated dose is given IV over 20–30 minutes and the remainder added to the intravenous fluids. The dose required varies between cases though, and should be adjusted according to response.

|l2=Acute Renal Failure#Treatment

</FlashCard>

</FlashCard>

[[Category:Feline Medicine Q&A]]

[[Category:Feline Medicine Q&A]]