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Ferrets (Laboratory) - Pathology (view source)
Revision as of 16:02, 2 March 2011
, 16:02, 2 March 2011→General GI
Gross lesions will include a marked dilation of the intrathoracic oesophagus together will ulcerations anywhere along it's length. Concurrent bronchopneumonia may also be present due to aspiration. Microscopic lesions are often inconclusive but can include muscle atrophy, hyperkeratosis of the epithelial lining and yeast within the mucosa resulting in a lymphocytic and neutrophilic inflammatory response.
Gross lesions will include a marked dilation of the intrathoracic oesophagus together will ulcerations anywhere along it's length. Concurrent bronchopneumonia may also be present due to aspiration. Microscopic lesions are often inconclusive but can include muscle atrophy, hyperkeratosis of the epithelial lining and yeast within the mucosa resulting in a lymphocytic and neutrophilic inflammatory response.
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'''Gastric Ulcers'''
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Ferrets are very susceptible to stress-related gastric ulcers. These are often associated with ''Helicobacter mustelae'' infections, see bacterial GI section below. Large ulcers may result in sudden death due to erosion of sub-mucosal blood vessels.
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There are two distinct types of gastric ulcer in ferrets. The most common is associated with the presence of digested blood in the lumen of the stomach. All types of ulcers will be pin point and difficult to see with the naked eye. They will be in highest numbers in the pylorus. Microscopic ulcer lesions will appear as full thickness areas of glandular necrosis and loss which are well demarcated from the surrounding tissue. Bleeding ulcers will be coated with a layer of brown haemoglobin pigment.
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===Bacterial===
===Bacterial===
'''Helicobacter mustelae'''
'''Helicobacter mustelae'''