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Ferrets (Laboratory) - Pathology (view source)
Revision as of 16:45, 4 March 2011
, 16:45, 4 March 2011→Respiratory System
Gross lesions will include multiple foci that coalesce to form a white to yellow subpleural pulmonary parenchyma. This parenchyma is of a very superficial nature. Microscopic lesions will include an aggregation of lipid-laden macrophages in the alveoli immediately subjacent to the pleura. Larger lesions will include moderate numbers of lymphocytes and cholesterol clefts.
Gross lesions will include multiple foci that coalesce to form a white to yellow subpleural pulmonary parenchyma. This parenchyma is of a very superficial nature. Microscopic lesions will include an aggregation of lipid-laden macrophages in the alveoli immediately subjacent to the pleura. Larger lesions will include moderate numbers of lymphocytes and cholesterol clefts.
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'''Aspiration Pneumonia'''
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Aspiration pneumonia is the most common cause of pneumonia in ferrets and is caused by either oral drug administration or vomiting. This is particularly common when administering oral drugs to ferrets due to their tendancy to fight/wriggle during administration.
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Gross lesions will include consolidation of the cranioventral lung lobes, either uni or bi-laterally. The severity of the lesions will be proportionate to the length of time since the aspiration occurred. In most cases minimal lesions will be visible but in severe and long-standing cases gangerenous, cavitated lesions may be seen within the pulmonary parenchyma. Microscopic findings may include primary lesions within the small airways. Bronchioles may contain a variable mixture of viable and degenerate neutrophils, sloughed epithelial cells and enosinophilic proteinaceous material (particularly if the aspirate is vomit based). There may also be a foamy accumulation of macrophages in surrounding alveoli. In long-standing cases there may be a pronounced granulomatous response with numerous foreign bodies. Where vomit has been aspirated there may also be extensive necrosis of the airways and surrounding alveoli with sloughing of the bronchiolar epithelium.#
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'''Influenza'''
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