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→Squamous mucosal defence mechanismsThe Equine Gastric Ulcer Council (1999) Tutorial Article: Recommendations for the diagnosis and treatment of equine gastric ulcer syndrome (EGUS). Equine Vet Educ, 11(5):262-272.
The squamous mucosa has comparatively few defence mechansims:
The squamous mucosa has comparatively few defence mechansims:
*'''Intercellular tight junctions''' and '''intracellular buffering systems''' act as barriers
*'''Intercellular tight junctions''' and '''intracellular buffering systems''' act as barriers
*'''Epidermal growth factor''' has also been found to contribute to the healthy maintenance and repair of gastric squamous epithelium (Jeffrey et al. 200 in(Martineau 2009)
*'''Epidermal growth factor''' has also been found to contribute to the healthy maintenance and repair of gastric squamous epithelium.<ref>Jeffrery, S.C, Murray, M.J, Eichorn, E.S (2001) Distribution of epidermal growth factor receptor (EGFr) in normal and acute peptic-injured equine gastric squaous epithelium. ''Equine Vet J'', 33:562-569. In: Martineau, H, Thompson, H, Taylor, D (2009) Pathology of gastritis and gastric ulceration in the horse. Part 1: range of lesions present in 21 mature individuals. ''Equine Vet J'', 41(7):638-644.</ref>
=====Other intrinsic defence mechanisms=====
=====Other intrinsic defence mechanisms=====