Difference between revisions of "Immunoglobulin D"

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(Created page with '{{review}} <br> <p>''Shortened to IgD''</p> thumb|150px|right|'''IgD''' thumb|right|150px|IgD - B. Catchpole, RVC 2008 <p>IgD is present in…')
 
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<center><b><sup>[[Immunoglobulins|Immunoglobulins]]: [[Immunoglobulin A|Immunoglobulin A]], [[Immunoglobulin D - WikiBlood|Immunoglobulin D]], [[Immunoglobulin E - WikiBlood|Immunoglobulin E]], [[Immunoglobulin G - WikiBlood|Immunoglobulin G]] & [[Immunoglobulin M - WikiBlood|Immunoglobulin M]]</sup></b></center>
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<center><b><sup>[[Immunoglobulins|Immunoglobulins]]: [[Immunoglobulin A|Immunoglobulin A]], [[Immunoglobulin D|Immunoglobulin D]], [[Immunoglobulin E - WikiBlood|Immunoglobulin E]], [[Immunoglobulin G - WikiBlood|Immunoglobulin G]] & [[Immunoglobulin M - WikiBlood|Immunoglobulin M]]</sup></b></center>

Revision as of 16:25, 12 June 2010



Shortened to IgD

IgD
IgD - B. Catchpole, RVC 2008

IgD is present in ruminants, pigs, (dogs) and rodents but has not been identified in horses, cats, rabbits and chickens. It is mainly expressed on the surface of B-cells i.e. it is never secreted.

Structure

IgD is Y-shaped and in rodents it has two heavy chain constant regions, whereas other mammals have three. IgD has a long hinge region and no disulfide bonds.

Function

  • IgD is only expressed in association with IgM
  • It is important in B-cell development.



Immunoglobulins: Immunoglobulin A, Immunoglobulin D, Immunoglobulin E, Immunoglobulin G & Immunoglobulin M