In Vitro Maturation - Anatomy & Physiology
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- Of interest for breeding guide dogs, which are monoetrous animals that do not produce many mature oocytes. This is desirable to avoid bitches having to take leave due to pregnancy.
- Experimental with low success rates.
- Routine in mice.
- Recovery of secondary or primary (ultimately primordial) follicles.
- Oocytes are arrested in the germinal vesicle stage (prophase of the first meiotic division).
- Follicles matured in vitro for subsequent IVF.
- Donor should be pre-pubertal, thus a full pool of primordial follicles is available.