Difference between revisions of "Mareks Disease"
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m (Text replace - "Category:To_Do_-_Viruses" to "Category:To_Do_-_Clinical/Viruses") |
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| − | {{unfinished}} | + | {{unfinished}} |
| − | Caused by a herpesvirus | + | Caused by a herpesvirus |
| + | |||
| + | ==== Hosts ==== | ||
| − | |||
*The most important disease of '''unvaccinated backyard chicken flocks''' | *The most important disease of '''unvaccinated backyard chicken flocks''' | ||
| − | ====Pathogenesis==== | + | ==== Pathogenesis ==== |
| − | *Replicates initially in the lungs and B cells | + | |
| − | *Enters feather follicles: produces virus-laden dander that is shed into litter | + | *Replicates initially in the lungs and B cells |
| − | *Reaches T cells, causing proliferation without virus protein production | + | *Enters feather follicles: produces virus-laden dander that is shed into litter |
| − | *T cells localize in brain or nerves causing '''encephalitis''' | + | *Reaches T cells, causing proliferation without virus protein production |
| + | *T cells localize in brain or nerves causing '''encephalitis''' | ||
*End stage: massive visceral tumors | *End stage: massive visceral tumors | ||
| − | ====Epidemiology==== | + | ==== Epidemiology ==== |
| + | |||
*More virulent strains evolving: presents a challenge to vaccinal immunity | *More virulent strains evolving: presents a challenge to vaccinal immunity | ||
| − | ====Control==== | + | ==== Control ==== |
| − | *Removal of litter between batches of chicks | + | |
| + | *Removal of litter between batches of chicks | ||
*'''Vaccines''' administered in ovo at 18 days | *'''Vaccines''' administered in ovo at 18 days | ||
| − | [[Category:Herpesviridae]][[Category: | + | |
| − | [[Category:To_Do_-_Clinical/Viruses]] | + | [[Category:Herpesviridae]] [[Category:Avian Viruses]] [[Category:To_Do_-_Clinical/Viruses]] |
Revision as of 17:00, 24 January 2011
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This article is still under construction. |
Caused by a herpesvirus
Hosts
- The most important disease of unvaccinated backyard chicken flocks
Pathogenesis
- Replicates initially in the lungs and B cells
- Enters feather follicles: produces virus-laden dander that is shed into litter
- Reaches T cells, causing proliferation without virus protein production
- T cells localize in brain or nerves causing encephalitis
- End stage: massive visceral tumors
Epidemiology
- More virulent strains evolving: presents a challenge to vaccinal immunity
Control
- Removal of litter between batches of chicks
- Vaccines administered in ovo at 18 days