Modified Transudate

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  • High cells and low protein OR Low cells and high protein
  • Yellow to serosanguinous, turbid
  • Specific gravity 1.018 - 1.030
  • Total protein 25 - 50g/L
  • Nucleated cells 0.3 - 5.5 x10e9/L (up to 7 x 10e9/L)
  • Mesothelial cells, macrophages, non-degenerate neutrophils, small lymphocytes
  • Due to:
    • Cardiac disease
      • Increased hydrostatic pressure within blood vessels
      • May be compounded by hypertension
    • Chylous effusions (see below)
    • Lymphatic obstruction (neoplasia - e.g. papillary adenocarcinoma of the ovary in the bitch, also produces fluid)