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Muscular Dystrophy

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  • Inherited group of degenerative muscular diseases
  • Progressive muscle weakness and wasting
  • Usually due to a genetic fault -> muscular protein deficiency
    • Duchenne MD in humans due to dystrophin deficiency also present in some animals
    • Dystrophin gene mutations reported in the Golden Retriever, Rottweiler, German shorthaired pointer and Irish terrier etc.
  • Inadequate regeneration, compensatory hypertrophy
  • More about Muscular dystrophy
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