Difference between revisions of "Newcastle Disease Virus"
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| − | + | Newcastle disease is a virus from the family '''Paramyxoviridae'''. Avian paramyxovirus 1 affects chickens, ducks, pheasants, geese and turkeys. The virus is stable in carcasses for weeks, so has the potential to affect a large amount of | |
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[[Image:Newcastle Disease.jpg|150px|thumb|right|'''Newcastle Disease (Copyright L. Mahin, Wikimedia Commons) ''']] | [[Image:Newcastle Disease.jpg|150px|thumb|right|'''Newcastle Disease (Copyright L. Mahin, Wikimedia Commons) ''']] | ||
Revision as of 14:48, 9 July 2010
Newcastle disease is a virus from the family Paramyxoviridae. Avian paramyxovirus 1 affects chickens, ducks, pheasants, geese and turkeys. The virus is stable in carcasses for weeks, so has the potential to affect a large amount of
Hosts
- Gallinaceous birds, pigeons, parrots, finches
- Subclinical carriers: ducks, ostriches
- Causes conjunctivitis in humans
Pathogenesis
- Transmission via aerosol and direct contact
- Disease ranges from subclinical respiratory tract infections -> torticollis -> haemorrhages and death
Diagnosis
Two diagnostic tests currently exist:
- Animal test:
- Samples of trachea and gut of 20 birds are tested in eggs
- HI using anti-NDV serum (to differentiate HA caused by Avian Influenza
- Virulence of isolate tested by the speed it kills chicks
- DNA test (which will soon replace the animal test):
- Sequencing the cleavage site of H gene
- The more basic amino acids the more virulent the virus
Control
- Newcastle Disease is NOTIFIABLE
- Vaccination of chickens and racing pigeons
- Surveillance of imported exotic birds
- Isolation of infected stock
- Infected premises to be culled and firebreak cull if spread