Changes

Due to the lytic nature of the group of drugs they are considered to be '''bacteriocidal''' (ie kill bacteria) and time dependent killers.

Due to the lytic nature of the group of drugs they are considered to be '''bacteriocidal''' (ie kill bacteria) and time dependent killers.

==Spectrum of Activity==

==Spectrum of Activity==

If a beta-lactamase inhibitor ('''Clavulanic acid''') is added to the drug formulation, the spectrum of most sub-groups is extended.

If a beta-lactamase inhibitor ('''Clavulanic acid''') is added to the drug formulation, the spectrum of most sub-groups is extended.

==Pharmacokinetic Considerations==

==Pharmacokinetic Considerations==

* '''Carboxypenicillins''' - unstable in acid. Route of admin: IM or IV.

* '''Carboxypenicillins''' - unstable in acid. Route of admin: IM or IV.

==Side Effects and Contraindications==

==Side Effects and Contraindications==