Difference between revisions of "Peritoneal Cavity - Anatomy & Physiology"

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===Peritoneal Fluid===
 
===Peritoneal Fluid===
*A thin film of fluid is located between the two layers of peritoneum.
+
*The potential space formed by the two layers of peritoneum is filled with a thin film of fluid that allows the two layers to slide over each other freely.
 
*In equilibrium with plasma but doesn't contain high molecular weight molecules like fibrinogen.
 
*In equilibrium with plasma but doesn't contain high molecular weight molecules like fibrinogen.
  

Revision as of 12:05, 23 July 2008

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Introduction

The peritoneum is the serous membrane that lines the abdominal cavity. It lies directly beneath the abdominal musculature (rectus abdominis and transverse abdominis). It is a type of loose connective tissue and is covered by mesothelium. Extensions of the peritoneum form the mesentries, omenta and ligaments that support the abdominal contents. The peritoneum produces fluid to lubricate abdominal viscera. The peritoneum also enhances immune responses and walls off infection in the abdomen to prevent peritonitis.

Development

In the early embryo, the primitive gut tube is suspended by the dorsal and ventral mesogastria. The mesogastria divide the embryo into two cavities, called the left and right coelomic cavities. The ventral mesogastrium atrophies caudal to the pylorus of the stomach and cranial to the rectum. This gives the entire small intestine and most of the large intestine large scope for expansion and rotation. It also allows the left and right coelomic cavities coalesce. This forms one cavity; the peritoneal cavity. Peritoneal structures develop from the dorsal and ventral mesogastria.

Structure & Histology

  • Lining the abdomen is a thin layer of loose connective tissue covered by a single layer of mesothelial cells. The layer of mesothelial cells is referred to as the peritoneum. Collectively, the connective tissue and peritoneum are referred to as the serosa.
    • Mesothelial cells are simple squamous and of mesodermal origin.
      • Have microvilli on their surface.
      • Very fragile but regenerate very quickly.
  • A small amount of fibroelastic tissue is present within the connective tissue layer to provide support.
  • There are two layers of peritoneum lining the abdomen.
    • The layer in contact with the abdominal wall is called the parietal layer.
    • The layer covering the abdominal viscera is called the visceral layer.
    • The small space within these two layers is called the peritoneal cavity.
    • NB: In reality there are no viscera located in the peritoneal cavity. However the cavity created by the serosa is also confusingly referred to as the peritoneal cavity, and contains most abdominal contents.
  • The peritoneum evaginates to extend into the inguinal canals.
  • Many species have lymphoid tissue aggregates and fixed phagocytes in the omentum that are not covered by mesothelial cells
  • The peritoneum is smooth and clear in the healthy animal.
  • NB: Post mortem change and autolysis result in increased volumes of red-brown fluid in the abdomen, not associated with other pathology, no roughening of surfaces of organs or peritoneum.

Peritoneal Fluid

  • The potential space formed by the two layers of peritoneum is filled with a thin film of fluid that allows the two layers to slide over each other freely.
  • In equilibrium with plasma but doesn't contain high molecular weight molecules like fibrinogen.

Function

  • Secretes a small volume of clear fluid for lubrication
    • Allows the abdominal viscera to move around by reducing the friction between them.
      • High fibrinolytic activity to protect against the formation of adhesions.
  • Provides a route for entry of blood and nerve and lymphatics

Types of Peritoneum

Terminology:

  • Mesentry: attaches viscera to the dorsal abdominal wall.
  • Omentum: from the stomach to other viscera.
  • Ligament: from viscera not involved in digestion to the abdominal wall or to other viscera that are not involved in digestion (e.g.ligaments of the liver).

Intraperitoneal Organs

Retroperitoneal Organs

Species Differences

  • Small animals
    • Low volume of clear straw coloured fluid
    • Specific gravity <1.015 to 1.018
    • Total protein 25-39g/L
    • Nucleated cell count <3x10e9/L
    • Mesothelial cells/macrophages

Links

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