921 bytes added ,  16:36, 22 November 2008
Line 25: Line 25:     
'''Life Cycle'''
 
'''Life Cycle'''
 +
*Incubation phase lasts 1 week
   −
'''Pathogenesis'''
+
*Lymphoblast proliferation
 +
**Local [[Lymph Nodes - Anatomy & Physiology|lymph node]] first infected then spreads through body
 +
**Occurs in week two
 +
 
 +
*Lymphoid depletion
 +
**[[Lymphocytes - WikiBlood|Lymphocytes]] killed
 +
**Decreases lymphopoiesis
 +
**Occurs in week 3
 +
 
 +
*Total incubation period takes about 18 days
    
'''Diagnosis'''
 
'''Diagnosis'''
 +
*Clinical signs
 +
**Pyrexia
 +
**Enlarged local [[Lymph Nodes - Anatomy & Physiology|lymph node]]
 +
***Usually parotid [[Lymph Nodes - Anatomy & Physiology|lymph node]] as [[Suborder: Metastigmata, ticks#Ticks of Veterinary Importance|''Rhipicephalus appendiculatus'']] feeds in the ear
 +
**Loss of condition
 +
 +
*Examine Giemsa stained smears of:
 +
**Local lymph node aspirated for schizonts
 +
**Blood smears for pioplasms in red blood cells
 +
 +
*Post-mortem
 +
**Pulmonary oedema
 +
**Gut mucosal haemorrhages
 +
**[[Lymph Nodes - Anatomy & Physiology|Lymph node]] and [[Spleen - Anatomy & Physiology|spleen]] cellular atrophy
    
'''Control'''
 
'''Control'''
3,326

edits