Difference between revisions of "Porcine Brucellosis"

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== Introduction ==
  
**Caused by [[Brucella suis|''B. suis'']]
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**Prolonged bacteraemia
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**Chronic inflammation in reproductive organs of boars and sows; also in joints and bones
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Porcine brucellosis is caused by the organism [[Brucella suis|''Brucella. suis'']] and is prevelant in pigs in Europe, Australia and Asia. It is, however, absent for the UK and Ireland.
**Routes of infection: ingestion or venereal
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**Abortion, still birth, neonatal mortality, temporary sterility
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Infection is via the faeco- oral route or the venereal route and transmission is due to introduction of live pigs with the disease or infected semen or ova. Lateral spread may also occur in younger pigs. Sows may remain carriers of the disease for many months and pass this on to up to 10% of their progeny.
**Boars excreting bacteria in semen may have testicular abnormalities or be normal
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**Lameness, incoordination and posterior paralysis in joint and bone involvement
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**Rose Bengal and indirect ELISA for diagnosis
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**Test and slaughter where exotic[[Category:To_Do_-_Kate]]
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== Clinical Signs ==
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Depend on when the infection occurs. Sows infected at service (by infected semen) will abort in the first trimester, whereas sows infected during pregnancy will usually produce mummified, stillborn or weak pigs depending on which stage of pregnancy the infection occured. Endometritis and vulval discharge are other signs that may be seen.
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In males, testicular abnormalities may be seen if they are excreting the bacteria in semen, such as enlargement and abnormal shape. Orchitis and epididymitis will occur 7 week after infection and then testicular atrophy may be present within 3 months.
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Joints and bones may be involved in both sexes which may cause lameness and swelling. this can be severe enough to warrant their destruction on humane grounds.
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== Diagnosis ==
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Isolation of the organism from lymph nodes and culturing, is a common diagnostic tool. Large scale surveilence is best performed using the Rose Bengal test plate and indirect ELISA.
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A PCR has been used but some infected animals are antibody negative.
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== Control ==
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Testing then slaughter is required immediately when the disease is exotic.
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[[Category:To_Do_-_Review]]

Revision as of 12:33, 4 March 2011

Introduction

Porcine brucellosis is caused by the organism Brucella. suis and is prevelant in pigs in Europe, Australia and Asia. It is, however, absent for the UK and Ireland.

Infection is via the faeco- oral route or the venereal route and transmission is due to introduction of live pigs with the disease or infected semen or ova. Lateral spread may also occur in younger pigs. Sows may remain carriers of the disease for many months and pass this on to up to 10% of their progeny.


Clinical Signs

Depend on when the infection occurs. Sows infected at service (by infected semen) will abort in the first trimester, whereas sows infected during pregnancy will usually produce mummified, stillborn or weak pigs depending on which stage of pregnancy the infection occured. Endometritis and vulval discharge are other signs that may be seen.

In males, testicular abnormalities may be seen if they are excreting the bacteria in semen, such as enlargement and abnormal shape. Orchitis and epididymitis will occur 7 week after infection and then testicular atrophy may be present within 3 months.

Joints and bones may be involved in both sexes which may cause lameness and swelling. this can be severe enough to warrant their destruction on humane grounds.


Diagnosis

Isolation of the organism from lymph nodes and culturing, is a common diagnostic tool. Large scale surveilence is best performed using the Rose Bengal test plate and indirect ELISA.

A PCR has been used but some infected animals are antibody negative.


Control

Testing then slaughter is required immediately when the disease is exotic.