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==Pathogenesis==
 
==Pathogenesis==
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Once PRRS virus gains entry to the host, primary replication occurs in regional or mucosal macrophages such as in the tonsil and the nasal and respiratory epithelium. After around twelve hours, viraemia occurs and the virus is disseminated systemically. Lymphatic transport
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Once PRRS virus gains entry to the host, primary replication occurs in regional or mucosal macrophages such as in the tonsil and the nasal and respiratory epithelium. After around twelve hours, viraemia occurs and the virus is disseminated systemically.  
of PRRS virus and virus-infected macrophages to
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regional lymph nodes is also thought to occur.
   
Secondary replication of PRRS virus occurs in monocyte/
 
Secondary replication of PRRS virus occurs in monocyte/
 
macrophages in many tissues. While other cell
 
macrophages in many tissues. While other cell
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