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New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Parvoviridae |subtext1=PARVOVIRUSES |pagetype =Bugs }} <br> ====Antigenicity==== *Single serotype ====Hosts==== ...
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{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Parvoviridae
|subtext1=PARVOVIRUSES
|pagetype =Bugs
}}
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====Antigenicity====
*Single serotype

====Hosts====
*Pigs

====Pathogenesis====
*Principal viral cause of '''SMEDI syndrome''': Stillbirths, Mummification, Embryonic Deaths, and Infertility
*Replicates in alimentary epithelium followed by viremia
*Often '''no clinical signs in breeding and growing stock'''
*'''Transplacental''' infection occurs in early pregnancy, with some (but not all) surviving piglets living as carriers

====Epidemiology====
*About 50% of UK pigs are antibody-positive
*Transfer is '''orofecal''' or via '''fomites'''
*Outbreaks occur as herd is developing immunity
*Congenitally infected piglets act as herd '''reservoir'''

====Diagnosis====
*'''Immunostaining''' of fetal tissues
*Virus isolation in cell culture
*HA on feces
*'''Rising antibody titres''' in paired serum sample by HAI

====Control====
*Inactivated vaccine (UK) or live attenuated (USA)
*Infected piglets should be culled
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