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==Signalment and Description==
 
==Signalment and Description==
===Hepatocellular Tumours ([[Liver Proliferative - Pathology #Hepatocytic|Hepatocellular carcinomas]] (HCC) and [[Liver Proliferative - Pathology #Hepatocytic|Hepatomas]])===
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===Hepatocellular Tumours ([[Carcinoma#Hepatocytic|Hepatocellular carcinomas]] (HCC) and [[Adenoma#Hepatocytic|Hepatomas]])===
 
* HCC occurs more frequently in dogs and hepatomas more commonly in cats. They are the most common primary liver tumour in dogs and the second most common in cats.  
 
* HCC occurs more frequently in dogs and hepatomas more commonly in cats. They are the most common primary liver tumour in dogs and the second most common in cats.  
 
* Male dogs over 10 years old are the most frequently affected by HCC and Miniature schnauzers may have a breed predisposition.
 
* Male dogs over 10 years old are the most frequently affected by HCC and Miniature schnauzers may have a breed predisposition.
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* Metastatic rate for dogs with massive HCC: 0-37%
 
* Metastatic rate for dogs with massive HCC: 0-37%
 
* Metastatic rate for dogs with nodular and diffuse HCC: 93-100%
 
* Metastatic rate for dogs with nodular and diffuse HCC: 93-100%
* [[Liver Proliferative - Pathology #Hepatocytic|Hepatomas]]) are usually incidental findings and non-significant
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* [[Adenoma#Hepatocytic|Hepatomas]]) are usually incidental findings and non-significant
    
===Cholangiocellular Tumours (Bile duct carcinomas and adenomas)===
 
===Cholangiocellular Tumours (Bile duct carcinomas and adenomas)===
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* Primary tumours are aggressive and often affect more than one liver lobe and metastasise most frequently to the regional lymph nodes, the lungs and peritoneum.  
 
* Primary tumours are aggressive and often affect more than one liver lobe and metastasise most frequently to the regional lymph nodes, the lungs and peritoneum.  
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===Sarcomas ([[Liver Proliferative - Pathology #Haemangiosarcoma|Haemangiosarcoma]] (HSA), Leiomyosarcoma, Fibrosarcoma)===
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===Sarcomas ([[Haemangiosarcoma|Haemangiosarcoma]] (HSA), Leiomyosarcoma, Fibrosarcoma)===
 
* HSA is the most common hepatic sarcoma in cats
 
* HSA is the most common hepatic sarcoma in cats
 
* Leiomyosarcoma is the most common hepatic sarcoma in dogs
 
* Leiomyosarcoma is the most common hepatic sarcoma in dogs
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==Treatment==
 
==Treatment==
 
===Surgery===
 
===Surgery===
Surgical excision is advised for hepatic adenomas, bile duct adenomas and massive [[Liver Proliferative - Pathology #Hepatocytic|hepatocellular carcinomas]]. Nodulectomy or lobectomy can be used for focal tumours of one or more lobes. Diffuse tumours and widespread nodular disease carry a worse prognosis.
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Surgical excision is advised for hepatic adenomas, bile duct adenomas and massive [[Carcinoma#Hepatocytic|hepatocellular carcinomas]]. Nodulectomy or lobectomy can be used for focal tumours of one or more lobes. Diffuse tumours and widespread nodular disease carry a worse prognosis.
    
===Chemotherapy===
 
===Chemotherapy===
Not currently recommended for primary hepatic neoplasia. Some metastatic sarcomas, for example [[Liver Proliferative - Pathology #Haemangiosarcoma|haemangiosarcomas]], may show some response.
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Not currently recommended for primary hepatic neoplasia. Some metastatic sarcomas, for example [[Haemangiosarcoma|haemangiosarcomas]], may show some response.
    
===Radiotherapy===
 
===Radiotherapy===
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==Prognosis==
 
==Prognosis==
The mean survival time for massive [[Liver Proliferative - Pathology #Hepatocytic|hepatocellular carcinomas]] following surgery is approximately 1 year. Otherwise the prognosis is poor for other malignant and metastatic tumours. If successfully excised the prognosis for benign tumours is good.
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The mean survival time for massive [[Carcinoma#Hepatocytic|hepatocellular carcinomas]] following surgery is approximately 1 year. Otherwise the prognosis is poor for other malignant and metastatic tumours. If successfully excised the prognosis for benign tumours is good.
     
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