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→T-cell receptors
==T-cell receptors==
==T-cell receptors==
[[Image:T Cell diagram 2.jpg|thumb|right|325px|T Cell - Copyright Prof Dirk Werling DrMedVet PhD MRCVS]]
T-cell receptors are the antigen-specific receptors for T-lymphocytes, and are a combination of either &alpha/&beta chains or &gamma/&delta chains; one T-cell will express either &alpha/&beta or &gamma/&delta TCRs. The antigen-binding site of the TCR is produced by a combination of the V domains of the relevant chain. Like antibody, the specificity of the TCR is determined by the '''amino acid composition of the variable domains'''.
T-cell receptors are the antigen-specific receptors for T-lymphocytes, and are a combination of either &alpha/&beta chains or &gamma/&delta chains; one T-cell will express either &alpha/&beta or &gamma/&delta TCRs. The antigen-binding site of the TCR is produced by a combination of the V domains of the relevant chain. Like antibody, the specificity of the TCR is determined by the '''amino acid composition of the variable domains'''.
TCRs are linked to the cell membrane; structurally, they look like a single arm of an antibody molecule consisting of a distal domain and a membrane proximal constant domain
TCRs are linked to the cell membrane; structurally, they look like a single arm of an antibody molecule consisting of a distal domain and a membrane proximal constant domain
==Helper CD4+==
==Helper CD4+==