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Type II Hypersensitivity
(view source)
Revision as of 15:54, 29 August 2008
258 bytes added
,
15:54, 29 August 2008
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==Introduction==
==Introduction==
−
Production of IgM or IgG to cell surface antigens or extracellular matrix proteins.
+
Production of
[[Immunoglobulin M - WikiBlood|
IgM
]]
or
[[Immunoglobulin G - WikiBlood|
IgG
]
to cell surface antigens or extracellular matrix proteins.
==Mechanism==
==Mechanism==
Line 25:
Line 25:
1. Antibody dependent cell cytotoxicity (ADCC)
1. Antibody dependent cell cytotoxicity (ADCC)
−
* Pemphigus vulgaris
+
*
[[Autoimmune Diseases - WikiBlood|
Pemphigus vulgaris
]]
−
* Bullous pemphigoid
+
*
[[Autoimmune Diseases - WikiBlood|
Bullous pemphigoid
]]
−
2. Complement mediated lysis
+
2.
[[
Complement
- WikiBlood|Complement]]
mediated lysis
−
* Self RBC antigen:
+
* Self
[[Erythrocytes - WikiBlood|
RBC
]]
antigen:
−
** Immune mediated haemolytic anaemia
+
**
[[Autoimmune Diseases - WikiBlood|
Immune mediated haemolytic anaemia
]]
−
* Foreign RBC:
+
* Foreign
[[Erythrocytes - WikiBlood|
RBC
]]
:
** Blood transfusion reaction
** Blood transfusion reaction
** Haemolytic disease of new born (Rhesus disease in humans and neonatal isoerythrolysis in foals and kittens)
** Haemolytic disease of new born (Rhesus disease in humans and neonatal isoerythrolysis in foals and kittens)
Mmadment
469
edits