Difference between revisions of "Vitamin K Deficiency"

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==Introduction==
 
==Introduction==
 
The absolute or relative deficiency of vitamin K can give rise to defective coagulation.
 
The absolute or relative deficiency of vitamin K can give rise to defective coagulation.
Anticoagulant rodenticide toxiticy is one of the most common causes of acquired coagulopathy in small animals. Warfarin itself has a short half-life and a fairly low toxicity in non-rodent species, so unless large or repeated doses are consumed clinical bleeding is rare. However, the second generation anticoagulant rodenticides are far more potent, and it is possible for a domestic animal to acquire secondary poisoning by ingesting a killed rodent<sup>1</sup>.  
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Anticoagulant rodenticide toxiticy is one of the most common causes of acquired coagulopathy in small animals. Warfarin itself has a short half-life and a fairly low toxicity in non-rodent species, so unless large or repeated doses are consumed clinical bleeding is rare. However, the second generation anticoagulant rodenticides are far more potent, and it is possible for a domestic animal to acquire secondary poisoning by ingesting a killed rodent<sup>1</sup>. Dogs are most commonly effected, but predator species such as cats and owls do occaionally suffer from secondary poisonings.
  
  

Revision as of 18:32, 2 October 2010

Introduction

The absolute or relative deficiency of vitamin K can give rise to defective coagulation. Anticoagulant rodenticide toxiticy is one of the most common causes of acquired coagulopathy in small animals. Warfarin itself has a short half-life and a fairly low toxicity in non-rodent species, so unless large or repeated doses are consumed clinical bleeding is rare. However, the second generation anticoagulant rodenticides are far more potent, and it is possible for a domestic animal to acquire secondary poisoning by ingesting a killed rodent1. Dogs are most commonly effected, but predator species such as cats and owls do occaionally suffer from secondary poisonings.


References

Also see Anticoagulant Rodenticide Toxicity