Category:Intestine - Vascular Disturbances

Vascular disturbances cause obstruction of efferent veins, blockage of afferent arteries or reduced blood flow through unobstructed circulation. All have similar effects on the intestine.

Effects of Intestinal Hypoxia

• Intestinal hypoxia is induced by vasular distrubances (above).
• Timescale:
  • 10 – 30 minutes - separation of epithelium from basement membrane.
  • 1 - 2 hours - villus destruction.
  • 2 hours - necrosis of crypt cells.
  • 4 - 5 hours - all mucosa necrotic, sloughed.