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  • Also called Aseptic necrosis or Ischaemic necrosis
  • Degeneration and necrosis of osseous tissue
  • Due to bone marrow pressure and ischaemia resulting from
  • Grossly:
    • Necrotic bone difficult to recognise
    • Sometimes, periosteum becomes dry, dull and detaches easily
    • On longitudinal section
      • Yellow-white necrotic bone
      • Scattered cancellous and endosteal bone
  • Histologically:
  • Necrotic bone is slowly resorbed, sequstered or covered by new woven bone
  • Persists
  • May not be detected radiographically
  • Associated with Calve-Legg Perthe's disease