6,502
edits
Changes
Jump to navigation
Jump to search
Complement Associated Diseases (view source)
Revision as of 09:37, 7 September 2007
, 09:37, 7 September 2007→Complement Associated Diseases
==Complement Associated Diseases==
==Complement Associated Diseases==
Most diseases associated with complement are linked to deficiencies of certain components. Deficiencies of components like C1, C2, C4, CR1 and DAF lead to autoimmune disease resulting from the inefficient removal immune complexes. This causes these complexes to lodge in many of the small capillary beds and induce inflammation. Most commonly this brings about such diseases as glomerulonephritis, vasculitis, rheumatoid arthritis and inflammation/irritation of the skin, for instance Systemic Lupus Erythematosis.
* Most diseases associated with complement are linked to deficiencies of certain components.
* Some deficiencies give inefficient removal of immune complexes, resulting in autoimmune disease.
Deficiencies of components like C1, C2, C4, CR1 and DAF lead to autoimmune disease resulting from the inefficient removal immune complexes. This causes these complexes to lodge in many of the small capillary beds and induce inflammation. Most commonly this brings about such diseases as glomerulonephritis, vasculitis, rheumatoid arthritis and inflammation/irritation of the skin, for instance Systemic Lupus Erythematosis.