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Neurogenesis - Anatomy & Physiology (view source)
Revision as of 10:57, 2 January 2011
, 10:57, 2 January 2011no edit summary
==Introduction==
==Introduction==
==Neural Crest==
==Neural Crest==
[[Image:neual crest.png|right|thumb|250px|Mithril 2010 Cross section scheme of vertebrate embryo. 1 – neural crest, 2 – neural tube, 3 – dorsal somite, 4 – notochord. Both paths of the neural crest cells migation marked by arrows: red one is the dorsolateral path, blue one signs the ventromedial path.
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The crest neuroectoderm is the region at the junction of epidermis and neural plate. When the neural tube closes, the epidermis is brought into contact with the crest neuroectoderm. This contact causes cells of the crest neuroectoderm to undergo an epithelial to mesenchymal transition. Cells that undergo this transition break away from the neuroectoderm and are called '''neural crest cells'''. The peripheral nervous system (PNS) develops from the neural crest. The undifferentiated neural crest cells migrate away from the neural tube along "pathways". These pathways are governed by repulsive cues from ther cells, as well as proliferation and survival signals, they differentiate once they reach their destination. Other non - neural tissues also develop from the neural crest. The type of tissue that neural crest forms is dependant on the origination of the cell along the anterior - posterior axis:
The crest neuroectoderm is the region at the junction of epidermis and neural plate. When the neural tube closes, the epidermis is brought into contact with the crest neuroectoderm. This contact causes cells of the crest neuroectoderm to undergo an epithelial to mesenchymal transition. Cells that undergo this transition break away from the neuroectoderm and are called '''neural crest cells'''. The peripheral nervous system (PNS) develops from the neural crest. The undifferentiated neural crest cells migrate away from the neural tube along "pathways". These pathways are governed by repulsive cues from ther cells, as well as proliferation and survival signals, they differentiate once they reach their destination. Other non - neural tissues also develop from the neural crest. The type of tissue that neural crest forms is dependant on the origination of the cell along the anterior - posterior axis: