This is the residual lumen of Rathke's Pouch and consists of of a series of small cystic cavities (follicles filled with colloid), with both basophillic and chromatophobic (poorly staining) cell types. These extend into the Pars Nervosa.
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This is the residual lumen of '''Rathke's Pouch''' and consists of of a series of small cystic cavities (follicles filled with colloid), with both basophillic and chromatophobic (poorly staining) cell types. These extend into the '''pars nervosa'''. In horses, '''melanotropes''' convert the [[Prohormones - Anatomy & Physiology|prohormone]] ''proopiomelanocorticotropin'' (POMC) to ''melanocyte Stimulating Hormone'' (a-MSH) and ''corticotropin-like intermediate lobe peptide'' (CLIP):
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In horses, '''Melanotropes''' convert the [[Prohormones - Anatomy & Physiology|prohormone]] ''Proopiomelanocorticotropin'' (POMC) to ''Melanocyte Stimulating Hormone'' (a-MSH) and ''Corticotropin-like Intermediate lobe Peptide'' (CLIP):
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'''POMC --> ACTH --> a-MSH + CLIP'''
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POMC --> ACTH --> a-MSH + CLIP
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Stage 1 uses the enzyme, '''Prohormone Convertase I''' and stage 2 uses the enzyme, '''Prohormone Convertase II'''. These processes are NOT under [[Negative Feedback - Anatomy & Physiology|negative feedback control]].
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Stage 1 uses the enzyme ''Prohormone Convertase I''.
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Stage 2 uses the enzyme ''Prohormone Convertase II''.
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These processes are NOT under [[Negative Feedback - Anatomy & Physiology|negative feedback control]].