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==Effects of Angiotensin II on Blood Pressure==

==Effects of Angiotensin II on Blood Pressure==

'''Angiotensin II''' acts on '''AT1 receptors''' to stimulate the release of '''[[Aldosterone|aldosterone]]''' from the [[Adrenal Glands - Anatomy & Physiology#Adrenal Glands|zona glomerulosa]] of the adrenal glands. This mineralocorticoid increases the reabsorption of sodium, and therefore water and chloride from the distal tubule of the kidney, thus helping to increase blood pressure and volume. It also stimulates the thirst center, and increases the secretion of [[Pituitary Gland - Anatomy & Physiology #Posterior Pituitary Gland |anti-diuretic hormone (ADH)]] to help increase blood volume. The RAAS allows pressure to return to 50% of baseline within 15 minutes of a significant haemorrhage occuring.

'''Angiotensin II''' acts on '''AT1 receptors''' to stimulate the release of '''[[Aldosterone|aldosterone]]''' from the [[Adrenal Glands - Anatomy & Physiology#Adrenal Glands|zona glomerulosa]] of the adrenal glands. This mineralocorticoid increases the reabsorption of sodium, and therefore water and chloride from the distal tubule of the kidney, thus helping to increase blood pressure and volume. It also stimulates the thirst center, and increases the secretion of [[Pituitary Gland - Anatomy & Physiology #Posterior Pituitary Gland |anti-diuretic hormone (ADH)]] to help increase blood volume. The RAAS allows pressure to return to 50% of baseline within 15 minutes of a significant haemorrhage occurring.

==Effects of Angiotensin II on GFR==

==Effects of Angiotensin II on GFR==

If blood pressure drops then [[Glomerular Apparatus and Filtration - Anatomy & Physiology#Glomerular Filtration Rate|glomerular filtration rate (GFR)]] also drops, due to reduced blood flow through the kidneys. To restore homeostasis, contraction of the efferent arteriole occurs in response to angiotensin II and the pressure difference between the afferent and efferent arterioles increases, creating greater filtration pressure. When blood pressure falls therefore, there is minimum alteration of GFR. The increased renal resistance to blood flow and the maintained GFR has many advantageous effects.   

If blood pressure drops then [[Glomerular Apparatus and Filtration - Anatomy & Physiology#Glomerular Filtration Rate|glomerular filtration rate (GFR)]] also drops, due to reduced blood flow through the kidneys. To restore homeostasis, contraction of the efferent arteriole occurs in response to angiotensin II and the pressure difference between the afferent and efferent arterioles increases, creating greater filtration pressure. Therefore, when blood pressure falls, there is minimum alteration of GFR. The increased renal resistance to blood flow and the maintained GFR has many advantageous effects.   

===Advantages of Angiotensin II induced Vasoconstriction===

===Advantages of Angiotensin II induced Vasoconstriction===

[[Category:Kidney Hormonal Regulators]][[Category:Endocrine System - Anatomy & Physiology]]

[[Category:Kidney Hormonal Regulators]][[Category:Endocrine System - Anatomy & Physiology]]

[[Category:Blood Pressure]]

[[Category:Blood Pressure]]

[[Category:To Do - AimeeHicks]]

[[Category:A&P Done]]

[[Category:To Do - Review]]