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Vascular Fluid Balance (view source)

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~~{{review}}~~

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~~{{toplink~~

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~~|linkpage =:Category:WikiPath~~

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~~|linktext =General Pathology~~

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~~|maplink = General Pathology (Content Map)~~

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~~|pagetype =Pathology~~

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~~|sublink1=Circulatory Disorders - Pathology~~

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~~|subtext1=CIRCULATORY DISORDERS~~

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==Introduction==

* Body fluid is composed of body water and the solutes dissolved within it.

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** Retained temporarily in tissues and slowly reabsorbed

** Absorbed by lymphatics.

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==Abnormal States of Sodium and Water Balance==

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** Cellular function is disrupted by imbalance.

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===Water Deficiency~~===~~

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===[[Water Deficiency]]===

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~~====Causes=~~===

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* '''Decreased intake'''.

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** The animal is disinclined or unabled to drink.

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** May be due to general debility or because of obstruction to the mouth/throuat by disease lesions.

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* '''Deprivation of water'''.

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** Animal loses access to its water supply.

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* '''Increased uncontrolled physiological loss'''

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** For example, due to hyperventilation, excessive sweating, or polyuria due to renal disease.

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~~====Effects====~~

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* Electrolytes are not depleted, although water is.

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** There is therefore an increase in osmolality of the extracellular fluid.

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*** Intracellular water is transferred to ECF, resulting in cellular dehydration results.

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**** Causes cell death.

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* Cellular dehydration particularly affects the CNS and heart.

===Deficiency of Both Sodium and Water===

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** Usually the result of dietary imbalance.

** Produces metastatic vascular calcification.

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[[Category:Circulatory Disorders - Pathology]]

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