Preferably, a full thickness intestinal biopsy should be taken to achieve a definitive diagnosis. Care should be taken as hypoproteinaemic animals are at much greater risk of dehiscence at the biopsy sites, potentially leading to an acute septic [[Peritonitis - Cats and Dogs|peritonitis]]. On histological examination of the biopsy sample, accumulation of lipid-laden macrophages may be detected together with a granulomatous response around distended lymphatics. | Preferably, a full thickness intestinal biopsy should be taken to achieve a definitive diagnosis. Care should be taken as hypoproteinaemic animals are at much greater risk of dehiscence at the biopsy sites, potentially leading to an acute septic [[Peritonitis - Cats and Dogs|peritonitis]]. On histological examination of the biopsy sample, accumulation of lipid-laden macrophages may be detected together with a granulomatous response around distended lymphatics. |