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− | ===Pigmentation=== | + | ===[[Muscle Pigmentation]]=== |
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− | *[[Pigmentation - Pathology#Lipofuscin|'''Lipofuscin''']]
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− | **Wear and tear pigment accumulating in secondary lisosomes -> converted into compact residual bodies
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− | **Due to old age, past or recent cachexia or starvation
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− | **Mostly stored in skeletal muscle of old high producing dairy cattle
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− | **Masseters and diaphragm mainly involved
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− | **No clinical importance
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− | **Histologically:
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− | ***Rounded yellow to brown granules at both poles of nucleus of the skeletal myofiber
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− | *[[Pigmentation - Pathology#Melanin|'''Melanin''']]
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− | **As part of congenital melanosis of calves in fascial sheaths and epimysium
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− | **Grossly - black foci
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− | *'''Myoglobin'''
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− | **After extensive muscle necrosis - '''rhabdomyolysis'''
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− | **Leaks to adjacent tissue after sudden injury
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− | *May also be present after some types of intramuscular injections e.g. iron dextran or tetracycline
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− | [[Category:Muscles - Degenerative Pathology]]
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