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| − | ===Ossification=== | + | ===[[Muscle Ossification]]=== |
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| − | *Metaplasia of muscle to bone
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| − | *'''Localised'''
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| − | **Only in single muscle or a single group of muscles
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| − | **May be associated with trauma
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| − | **Seen in horses and dogs
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| − | **Histologically:
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| − | ***Central zone - proliferating undifferentiated cells and [[Chronic Inflammation - Introduction#Fibroblasts|fibroblasts]]
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| − | ***Middle zone - [[Bones - Anatomy & Physiology|osteoblasts]] depositing osteoid and bone
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| − | ***Outer zone - [[Bones - Anatomy & Physiology|trabecular bone]] remodelled by [[Bones - Anatomy & Physiology|osteoclasts]]
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| − | *'''Progressive''' (fibrodysplasia ossificans progressiva)
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| − | **In connective tissue associated with skeletal muscle
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| − | **Secondary involvement of muscle tissue
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| − | **In pigs and cats
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| − | **Histologically:
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| − | ***Bundles of dense fibrous connective tissue
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| − | ***May contain accumulations of cartilage, bone or calcium
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| − | **Hyperplastic connective tissue -> compression of adjacent skeletal muscle -> [[Muscles Degenerative - Pathology#Atrophy|atrophy]]
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| − | [[Category:Muscles - Degenerative Pathology]]
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