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Ferrets (Laboratory) - Pathology (view source)
Revision as of 17:43, 4 March 2011
, 17:43, 4 March 2011→Integument System
==Integument System==
==Integument System==
'''Neoplasia'''
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Neoplasia is the most common skin problem in ferrets, where the incidence of neoplasia increases with age. There are a wide range of types of skin neoplasia found in ferrets with the two most common being sebaceous epithelioma and mast cell tumors. Dermal leiomyomas/leiomyosarcomas are also commonly seen in ferrets and commonly arise from smooth muscle associated with hair follicles (piloeimyomas). This condition most commonly affects the back and neck areas but can also be found anywhere on the body.
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Gross lesions for sebaceous epitheliomas will appear as warty, verrucous lesions that can arise anywhere on the animal's body, but are most often seen on the head and neck. Microscopic lesions for sebaceous epitheliomas will include an unencapsulated neoplasm composed of basal cells of which a small percentage will exhibit sebaceous and or squamous differentiation. These cells are reported to have no features of malignancy or metastatic abilities. Gross lesions for mast cell tumors will appear as flat, alopecic, hyperkeratotic plaques which are variably pruritic. Microscopic lesions will include a well demarcated, unencapsulated neoplasm that is commonly confined to the superficial dermis and will be composed of well differentiated mast cells. Small numbers of eosinophils will be scattered throughout the neoplasm. Vasculitis and/or collagen are rarely seen. Gross lesions for leiomyomas are often well encapsulated but have no metastatic potential.
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==Reproductive System==
==Reproductive System==