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Granulomatous Meningoencephalitis (view source)
Revision as of 12:53, 8 March 2011
, 12:53, 8 March 2011Created page with "(GME) * An idiopathic CNS conditon * May occur as: ** A disseminated disease ** A focal mass lesion ** A primary occular disease * Brain..."
(GME)
* An [[CNS Idiopathic Conditions - Pathology|idiopathic CNS conditon]]
* May occur as:
** A disseminated disease
** A focal mass lesion
** A primary occular disease
* Brainstem signs are common, although the forebrain is primarily affected.
* May be incorrectly diagnosed as lymphoma.
* Changes are apparent in the CSF.
** There is usually a mononucloear pleocytosis.
** Sometimes only protein is elveated.
* Diffuse inflammatory changes or a mass lesion will be seen by advanced imaging.
** However, biopsy is required for a definative diagnosis.
* Life span is between 6 months and 1 year from diagnosis.
====Treatment====
* Immunosuppression:
** Corticosteroids
** Azathioprine
** Cycophosphamide
* Surgery
** This is only appropriate if there is a focal mass.
* Radiation therapy.
[[:Category:CNS Non-Infectious Inflammatory Diseases]]
* An [[CNS Idiopathic Conditions - Pathology|idiopathic CNS conditon]]
* May occur as:
** A disseminated disease
** A focal mass lesion
** A primary occular disease
* Brainstem signs are common, although the forebrain is primarily affected.
* May be incorrectly diagnosed as lymphoma.
* Changes are apparent in the CSF.
** There is usually a mononucloear pleocytosis.
** Sometimes only protein is elveated.
* Diffuse inflammatory changes or a mass lesion will be seen by advanced imaging.
** However, biopsy is required for a definative diagnosis.
* Life span is between 6 months and 1 year from diagnosis.
====Treatment====
* Immunosuppression:
** Corticosteroids
** Azathioprine
** Cycophosphamide
* Surgery
** This is only appropriate if there is a focal mass.
* Radiation therapy.
[[:Category:CNS Non-Infectious Inflammatory Diseases]]