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Contagious Bovine Pleuropneumonia (view source)
Revision as of 15:00, 10 March 2011
, 15:00, 10 March 2011no edit summary
== Introduction ==
*Contagious Bovine Pleuropneumonia (CBPP) is a respiratory disease of cattle. It is notifiable in the UK and many other countries and has not been seen here for many years. It is transmitted by close contact with clinically or subclinically affected animals and severity depends on strain and host susceptibilit. There is usually around a 50% morbidity and high mortality rate in severe outbreaks.<br>
*Aerosol transmission by close contact with clinically or subclinically affected animals
*Diagnosis
**Clinical signs and post-mortem appearance
**PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage fluid
== Clinical signs ==
**Fluorescent antibody test
Clinical signs include an acute onset fever, anorexia, depression, lowered milk yield, hyperpnoea, coughing and a mucopurulent nasal dischargewhich all occur suddenly. Dyspnoea occurs with abducted elbows and extended necks and an expiratory grun. The disease can be fatal within 1-3 week.
Calves may suffer from [[Infectious Arthritis#In_Cattle|arthritis]], synovitis and endocarditi, but are most commonly seen as sudden death.
== Diagnosis ==
Clinical signs and history to suspect diagnosis but definative diagnosis should be achived by post mortem examination. Signs at necropsy will include marbled appearance to lungs with consolidated grey and red lobules separated by emphysematous areas
*Serofibrinous pleural fluid
*Necrotic foci surrounded by fibrous capsules in chronic cases act as source of infection
*Diagnosis
**Clinical signs and post-mortem appearance
**PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage fluid
**Fluorescent antibody test
**Serological tests such as serum agglutination, haemagglutination, complement fixation, ELISA
**Serological tests such as serum agglutination, haemagglutination, complement fixation, ELISA
*Treatment and control
*Treatment and control
**Slaughter of affected cattle in counries where the disease is exotic
**Slaughter of affected cattle in counries where the disease is exotic
**Movement restrictions, quaranteen and slaughter of carrier animals in endemic countries
**Movement restrictions, quaranteen and slaughter of carrier animals in endemic countries
*''M. mycoides'' subsp. 'mycoides'' causes septicaemia, pleuropneumonia, arthritis and mastitis in goats
*''M. mycoides'' subsp. 'mycoides''causes septicaemia, pleuropneumonia, arthritis and mastitis in goats''
**Vaccination in endemic regions
**Vaccination in endemic regions
*Caused by [[Mycoplasma mycoides subsp. mycoides|''Mycoplasma mycoides'']], small colony variant
*Caused by [[Mycoplasma mycoides subsp. mycoides|''Mycoplasma mycoides'']], small colony variant
*Causes a fibrinonecrotic [[Pneumonia Overview#Infectious causes of pneumonia|pneumonia]] and [[Pleuritis|fibrinous pleuritis]]
*Causes a fibrinonecrotic [[Pneumonia Overview#Infectious_causes_of_pneumonia|pneumonia]] and [[Pleuritis|fibrinous pleuritis]]
*Also affects caudodorsal areas
*Also affects caudodorsal areas
*[[Bronchopneumonia|Bronchopneumonia]] -> [[Lobar Pneumonia|lobar pneumonia]]
*[[Bronchopneumonia|Bronchopneumonia]] -> [[Lobar Pneumonia|lobar pneumonia]]
*Sequestra are common
*Sequestra are common
*NB: similarity to pneumonic pasteurellosis but CBPP has more pronounced marbled effect
*NB: similarity to pneumonic pasteurellosis but CBPP has more pronounced marbled effect
*Interstitial septa are markedly widened by fibrinous exudate and the necrotic areas may have a fibrous capsule
*Interstitial septa are markedly widened by fibrinous exudate and the necrotic areas may have a fibrous capsule
*Large colony variant will cause a similar disease in goats
*Large colony variant will cause a similar disease in goats
[[Category:Respiratory_Diseases_-_Cattle]] [[Category:To_Do_-_Kate]] [[Category:Respiratory_Bacterial_Infections]]
[[Category:Respiratory Diseases - Cattle]][[Category:To_Do_-_Kate]]
[[Category:Respiratory_Bacterial_Infections]]